KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
18.79
Human Site:
T1684
Identified Species:
34.44
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
T1684
L
P
P
H
I
K
S
T
V
S
V
Q
I
I
P
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
T1698
L
P
P
H
I
K
S
T
V
S
V
Q
I
I
P
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
T1684
L
P
P
H
I
K
S
T
V
S
V
Q
I
I
P
Dog
Lupus familis
XP_537704
2182
240593
T1692
L
P
P
H
I
K
S
T
V
S
V
Q
I
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S1683
P
H
I
K
S
T
V
S
V
Q
I
V
P
C
Q
Rat
Rattus norvegicus
NP_001100505
2040
223488
L1577
R
Q
I
Y
S
Q
H
L
K
S
L
A
F
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
T1680
L
P
S
N
I
K
S
T
V
S
V
Q
I
V
P
Chicken
Gallus gallus
XP_415884
2225
244861
I1735
L
P
P
N
I
K
N
I
I
S
V
Q
I
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
A1627
L
P
P
H
I
R
N
A
V
Y
V
Q
I
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
Q2126
V
P
D
S
V
R
S
Q
M
N
I
Q
I
I
S
Honey Bee
Apis mellifera
XP_393643
1982
216109
L1519
H
N
S
T
V
K
S
L
T
G
F
G
T
A
A
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
P2381
T
H
P
R
V
F
F
P
D
V
Y
K
S
A
S
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
R664
F
S
V
F
S
Q
C
R
R
F
Q
S
P
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
93.3
N.A.
6.6
6.6
N.A.
80
66.6
N.A.
73.3
N.A.
33.3
13.3
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
20
26.6
N.A.
93.3
93.3
N.A.
86.6
N.A.
73.3
20
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
8
0
16
16
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
8
8
0
0
8
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% G
% His:
8
16
0
39
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
54
0
0
8
8
0
16
0
62
39
8
% I
% Lys:
0
0
0
8
0
54
0
0
8
0
0
8
0
0
0
% K
% Leu:
54
0
0
0
0
0
0
16
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
16
0
0
16
0
0
8
0
0
0
0
0
% N
% Pro:
8
62
54
0
0
0
0
8
0
0
0
0
16
0
54
% P
% Gln:
0
8
0
0
0
16
0
8
0
8
8
62
0
0
8
% Q
% Arg:
8
0
0
8
0
16
0
8
8
0
0
0
0
0
0
% R
% Ser:
0
8
16
8
24
0
54
8
0
54
0
8
8
8
16
% S
% Thr:
8
0
0
8
0
8
0
39
8
0
0
0
8
8
0
% T
% Val:
8
0
8
0
24
0
8
0
54
8
54
8
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _